Polycystic Ovary Syndrome (PCOS) is a complex endocrine disorder in which androgen excess plays a central pathogenic role, driving both reproductive and metabolic dysfunction. Hyperandrogenism not only contributes to classic clinical features such as hirsutism, acne, and alopecia, but also disrupts follicular development, ovulation, and insulin signalling. Traditional treatment approaches have focused on symptom control rather than underlying mechanisms. However, growing insights into androgen biosynthesis, receptor signalling, and tissue-specific androgen action have led to significant advances in targeted therapeutic strategies. These developments offer new opportunities for more precise and effective management of PCOS.


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