Have you ever thought that the key to treating obesity might not just lie in the brain or fat cells but deep inside your gut?
I will be discussing the emerging research in metabolic medicine, the gut-derived bile acids and their powerful impact on weight regulation through receptors called FXR and TGR5.
Bile acids are substances made by our liver and stored in the gall bladder. Traditionally, we thought their only job was to help digest fats. But now we know that bile acids also act as powerful signalling molecules, influencing metabolism, inflammation and even energy expenditure.
Two key receptors respond to bile acids: FXR, short for Farnesoid X Receptor, and TGR5, also known as G-protein-coupled bile acid receptor 1.
Read the full article here: https://www.thelondonobesityclinic.co.in/can-gut-derived-bile-acids-fxr-tgr5-agonists-be-the-next-obesity-drug/
