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*In some cases, if the doctor requires more information, you may be asked to answer follow-up
questions or attend a 1-to-1 virtual consultation before a prescription is approved
*In some cases, if the doctor requires more information, you may be asked to answer follow-up questions or attend a 1-to-1 virtual consultation before a prescription is approved
Depression and obesity often coexist, creating a complicated relationship where each condition can
intensify the other. Those struggling with depression may experience weight gain, while individuals who are
overweight or obese face a greater likelihood of developing depressive feelings due to factors such as low
mood and reduced self-confidence.
The coexistence of depression and obesity can be attributed to various factors, including:
Depression and obesity often coexist, creating a complicated relationship where each condition can intensify the other. Those struggling with depression may experience weight gain, while individuals who are overweight or obese face a greater likelihood of developing depressive feelings due to factors such as low mood and reduced self-confidence.
The coexistence of depression and obesity can be attributed to various factors, including:
Obesity and depression are interconnected. According to a meta-analysis, obese individuals have 55% higher risk of developing depression whilst depressed individuals have 58% higher risk of becoming obese.
Obesity is an inflammatory condition where excess fat in the abdominal region releases pro-inflammatory cytokines, IL-6 and TNF-α and CRP. These cytokines can alter the brain neurotransmitters such as serotonin and dopamine, directly influencing mood. This altered brain chemistry creates a connection between depression and obesity.
Hormonal imbalances also contribute to this interlink. Obesity often leads to leptin and insulin resistance, impairing both appetite control and emotional regulation.
Elevated cortisol levels from chronic stress further promote fat storage and depressive symptoms. Environmental and lifestyle conditions also contribute.
Stigma, body shaming, and low self-esteem can activate stress pathways such as the HPA axis, reinforcing emotional eating and anxiety. Poor sleep, inactivity, and diets high in processed food can disrupt the gut-brain axis.
Mounjaro may be useful in managing depression and weight by
supporting weight management. Obesity and depression are linked. As
Mounjaro helps people with weight loss, the results may have a positive
effect on a persons wellbeing. After the doctor reviews the patient in a
consultation such as going over mental health, medications linked to
mental health, it will determine if the patient is suitable to be prescribed
Mounjaro. The patient would start on the starter dose of 2.5mg if
approved for Mounjaro.
Mounjaro may be useful in managing depression and weight by supporting weight management. Obesity and depression are linked. As Mounjaro helps people with weight loss, the results may have a positive effect on a persons wellbeing. After the doctor reviews the patient in a consultation such as going over mental health, medications linked to mental health, it will determine if the patient is suitable to be prescribed
Mounjaro. The patient would start on the starter dose of 2.5mg if approved for Mounjaro.
Mounjaro works by mimicking the effects of two natural hormones, glucose-dependent insulinotropic
polypeptide (GIP) and glucagon-like peptide-1 (GLP-1). These hormones help to control blood sugar
levels by increasing insulin secretion, slowing gastric emptying, and suppressing glucagon secretion.
Increasing insulin secretion: Mounjaro stimulates the release of insulin from the pancreas, which helps
to lower blood sugar levels
Slowing gastric emptying: Mounjaro slows down the movement of food from the stomach into the small
intestine, which helps you feel full for longer and eat less.
Suppressing glucagon secretion: Mounjaro reduces the release of glucagon from the pancreas, which
helps to prevent the liver from releasing too much sugar into the bloodstream.
Mounjaro works by mimicking the effects of two natural hormones, glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1). These hormones help to control blood sugar levels by increasing insulin secretion, slowing gastric emptying, and suppressing glucagon secretion.
Increasing insulin secretion: Mounjaro stimulates the release of insulin from the pancreas, which helps to lower blood sugar levels
Slowing gastric emptying: Mounjaro slows down the movement of food from the stomach into the small intestine, which helps you feel full for longer and eat less.
Suppressing glucagon secretion: Mounjaro reduces the release of glucagon from the pancreas, which helps to prevent the liver from releasing too much sugar into the bloodstream.
Before recommending Mounjaro for weight management, medical professionals will evaluate a number
of aspects, including general health and BMI. If the patient meets the eligibility requirements and the
medicine is deemed appropriate for managing their weight, they can be prescribed Mounjaro. There
maybe a few factors preventing the prescribing of Mounjaro such as Thyroid cancer or any medical
conditions which could be a health risk.
Before recommending Mounjaro for weight management, medical professionals will evaluate a number of aspects, including general health and BMI. If the patient meets the eligibility requirements and the medicine is deemed appropriate for managing their weight, they can be prescribed Mounjaro. There maybe a few factors preventing the prescribing of Mounjaro such as Thyroid cancer or any medical conditions which could be a health risk.
Read our articles on Wegovy & Mounjaro if you would like to learn more about the benefits, the research and case studies.
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*Disclaimer: Results may vary from person to person depending on individual engagement and commitment to the programme.
The content of this website is provided for general informational purposes only and is not intended as, nor should it be considered a substitute for, professional medical advice. Do not use the information on this website for diagnosing or treating any medical or health related condition. If you have or suspect you have a medical problem, promptly contact your healthcare provider.
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