Can Wegovy improve fertility?
Quick answer
Wegovy is not a fertility medicine, and evidence does not establish that semaglutide improves pregnancy or live-birth rates. Weight-related changes may affect ovulation for some people, but semaglutide should not be used during pregnancy; discuss conception plans and stopping treatment with your clinician.

Wegovy is not a proven fertility treatment and is not licensed to treat infertility. Weight management may support reproductive health for some people, but pregnancy cannot be promised. Do not use Wegovy during pregnancy or while trying to conceive, and stop it at least two months before a planned pregnancy.
Why are weight and fertility discussed together?
Weight can influence reproductive hormones and ovulation, the release of an egg. In some people with polycystic ovary syndrome (PCOS), a condition associated with irregular ovulation and hormonal changes, weight management may help menstrual patterns. Fertility also depends on many other factors, including age, sperm health and conditions affecting the reproductive organs.
Infertility is not your fault, and body weight alone does not explain it. Weight-related support should be sensitive and should not replace investigation of other causes or unnecessarily delay fertility advice.
What can Wegovy do, and what remains uncertain?
Wegovy contains semaglutide, which acts on glucagon-like peptide-1 (GLP-1), a hormone involved in appetite and blood sugar regulation. Its weight-management licence is for eligible people alongside dietary changes and physical activity. It is not a medicine that directly induces ovulation.
Evidence that a medicine supports weight loss is not evidence that it improves conception or live-birth outcomes. Studies focused on weight or menopausal symptoms cannot establish a fertility benefit. Any possible indirect reproductive benefit should be distinguished from a proven infertility treatment.
A clinician may consider weight management before pregnancy when appropriate, but the plan needs to account for your age, health, nutrition and fertility-treatment timetable. Wegovy is not suitable during attempts to conceive.
When should you stop before pregnancy?
UK product information advises stopping semaglutide at least two months before a planned pregnancy because it remains in the body for a long time. Use effective contraception during treatment and through the recommended interval after stopping, before trying to conceive. Discuss the timing with your prescriber and fertility team before starting treatment or changing contraception.
If you become pregnant while taking Wegovy, stop it and contact your clinician promptly. Limited safety information means it should not be used in pregnancy; accidental exposure does not by itself establish that harm has occurred. Your maternity team can advise on assessment and support. Wegovy should also not be used while breastfeeding.
If you have diabetes, arrange suitable blood sugar treatment before pregnancy rather than leaving the condition untreated.
Does Wegovy affect the contraceptive pill in the same way as Mounjaro?
No. The specific additional pill precaution for tirzepatide, sold as Mounjaro, does not apply to semaglutide. With Mounjaro, people using oral contraception should switch to a non-oral method or add a barrier method for four weeks after starting and for four weeks after every dose increase.
With either medicine, vomiting or severe diarrhoea can reduce the reliability of an oral contraceptive. Follow your pill’s illness and missed-pill instructions and ask a pharmacist or sexual health service if extra protection or emergency contraception is needed. Irregular periods do not reliably prevent pregnancy, and changes in ovulation can happen without being obvious.
What should a preconception discussion include?
Ask about the medication-free interval, folic acid, nutrition, other medicines, diabetes care where relevant and whether fertility assessment is needed now. If treatment stops, plan support for appetite and weight changes without blame or restrictive crash dieting. The aim is safe, coordinated care for your health and pregnancy plans, not a promised fertility outcome.
Sources & further reading

Reviewed by
Dr Chinnadorai Rajeswaran
Specialist Endocrinologist · MBBS MRCP FRCP
Last Reviewed: November 2026
Read about fertility concerns and related care.


