It starts with a consultation
Nothing is prescribed without one.
Medications
Foundayo
(Orforglipron)
Once-daily tablet — no needlesA once-daily tablet acting on the GLP-1 pathway — a needle-free option considered within specialist weight care.
Your care pathway
How treatment works here
A careful clinical assessment
A doctor reviews your medical history, current medicines, conditions and the factors driving your weight before any treatment is recommended.
Where treatment is appropriate
It is prescribed following your consultation. In the UK, treatment is dispensed by a licensed pharmacy and delivered to your address anywhere in the UK. In Chennai, it is collected in person from the clinic.
Reviewed before every supply
Nothing is issued on repeat without review. Before each supply you tell us how you are getting on, and a doctor reviews how you are responding, how you are tolerating treatment and anything that has changed before deciding.
What's Included
Your Foundayo Prescription Includes
Doctor-reviewed prescription
Every prescription follows individual review by a doctor and stays under ongoing clinical supervision.
Live online sessions with Dr Raj
Patients are invited to regular online education evenings and live Q&A sessions, covering nutrition, muscle preservation, managing side effects and planning for the long term.
Support between appointments
You can tell us about side effects or concerns at any point between consultations, not only at your next appointment.
How you receive your treatment
In the UK, dispensed by a licensed pharmacy and delivered to your door anywhere in the UK with tracked delivery. In Chennai, collected in person from the clinic.
About the Medication
What is Foundayo?
Foundayo contains orforglipron, a small-molecule medicine that activates the GLP-1 receptor. It is taken by mouth rather than by injection. Semaglutide (Wegovy) is also available as a tablet as well as a weekly injection, while tirzepatide (Mounjaro) is given by weekly injection only.
Because it is a non-peptide molecule it survives digestion, so it does not carry the strict food, water and timing rules of earlier oral GLP-1 tablets.
It is prescribed alongside a reduced-calorie diet and increased physical activity for adults who meet the licensed criteria. Suitability depends on your medical history, current medicines, pregnancy plans and the balance of potential benefit and risk.
How Does It Work?
Appetite regulation
Orforglipron acts on the same GLP-1 receptor as injectable medicines, influencing hunger, fullness and food intake.
Taken by mouth
One tablet daily, with or without food — the practical difference many patients care about most.
Metabolic monitoring
Appetite and weight changes can affect diabetes and blood-pressure medicines, so review remains part of treatment.
Taking the tablet
How a daily tablet changes the routine
The tablet route removes needles, sharps disposal and cold storage from the daily picture. What it does not remove is the need for review by a doctor.
- One tablet dailyTaken at the same time each day, with or without food.
- No injection techniqueNothing to prepare, prime or inject — and no sharps bin to manage.
- Room-temperature storageNo refrigeration, which makes travel simpler than with a pen.
- Stepwise escalationThe dose is increased in steps roughly every four weeks so your body can adjust.
- Daily consistency mattersA daily medicine relies on routine; missed days blunt the benefit more than with a weekly injection.
Clinical Evidence
How Effective is Foundayo?
In ATTAIN-1, adults with obesity or overweight and a weight-related condition received orforglipron or placebo alongside diet and activity support for 72 weeks. The study used hard capsules; the licensed film-coated tablet doses are different but have equivalent effects, as specified in the UK product information.
7.5%
5.5 mg tablet equivalent (6 mg capsule)
8.4%
9 mg tablet equivalent (12 mg capsule)
11.2%
17.2 mg tablet equivalent (36 mg capsule)
2.1%
Placebo at 72 weeks
Foundayo SmPC section 5.1, tables 2 and 3, ATTAIN-1 treatment-regimen estimand. Tablets and capsules are not interchangeable milligram for milligram. Study-group averages do not predict an individual result.
Dosing
How Do You Take Foundayo?
Foundayo is one tablet taken daily, with or without food. The dose is increased in steps so your body can adjust, and each increase follows clinical review.
Side effects are usually most noticeable in the days after a step up, which is why escalation is gradual rather than rushed.
Do not change your dose unless your doctor has told you to.
Available Doses
0.8mg
2.5mg
5.5mg
9mg
14.5mg
17.2mg
0.8mg is a starting dose only. Maintenance is individual — some patients settle at 9mg, others continue to the highest licensed dose where appropriate.
Who Qualifies?
- Adults meeting the licensed BMI and health criteria
- People who would prefer a tablet to a weekly injection
- A complete medical and medication review with no identified contraindication
- Not pregnant, breastfeeding or trying to conceive
Book a consultation
Discuss your care with the clinic that is right for you.
Potential Side Effects
Like all medicines, Foundayo may cause side effects. Most are mild and settle as your body adjusts. Seek urgent medical help for severe, persistent abdominal pain, especially if it spreads to the back, with or without vomiting.
NauseaVomitingDiarrhoeaConstipationReduced appetiteFatigueIndigestionHeadache
Always read the Patient Information Leaflet. Contact your clinic or your doctor with any concerns.
A Foundayo leaflet is not yet available in this library. Read the current patient leaflet supplied with your medicine, and ask your clinic or pharmacist for a copy before starting treatment.
Specialist Indications
How Foundayo is used across metabolic conditions
An oral GLP-1 opens the door for patients who will not or cannot use injections. Here is where it fits, with published evidence for each condition.
Complex severe obesity
Obesity with multiple interacting drivers, where adherence and daily routine matter as much as the molecule.
Read the condition pageWhere Foundayo fits: A needle-free option within a coordinated plan built after blood tests and root-cause assessment.
Published evidence
Type 2 diabetes
Insulin resistance and raised glucose alongside excess weight.
Read the condition pageWhere Foundayo fits: Glucose control often improves as weight reduces, so existing diabetes medicines are reviewed throughout treatment.
Published evidence
Needle anxiety and adherence
For many patients the barrier is not the medicine but the injection itself.
Where Foundayo fits: A daily tablet removes needles, sharps and refrigeration, which can make treatment possible where a pen was not.
Published evidence
Polycystic Ovary Syndrome (PCOS)
Polycystic Ovary Syndrome (PCOS) can involve insulin resistance, cycle disruption and androgen excess.
Read the condition pageWhere Foundayo fits: Weight and insulin sensitivity improvements may help cycle regularity; contraception and pregnancy plans are discussed first.
Published evidence
Fatty liver disease (MASLD)
Liver fat that responds to sustained weight reduction.
Read the condition pageWhere Foundayo fits: Considered alongside liver function tests and FibroScan monitoring as part of long-term liver care.
Published evidence
Maintenance after weight loss
Keeping a result is a different clinical task from achieving it.
Read the condition pageWhere Foundayo fits: A daily tablet can suit long-term maintenance, with review of dose, nutrition, protein intake and resistance exercise.
Published evidence
More than a prescription
The Specialist Weight Management Plan
The Specialist Weight Management Plan is our most intensive option for the most complex cases. Dr Raj recommends it after your initial consultation where it is the right level of support. Not everyone needs it. For others, consultations and review alone are enough, and what you are offered depends on what is actually going on.
Foundayo FAQs
From the clinic
Clinical Insights
Medication
Why can you take Foundayo with food when the other pill can't?
Foundayo (orforglipron) can be taken with or without food because it is a non-peptide small molecule, unlike oral semaglutide, which has specific absorption instructions. These directions are product-specific; follow the instructions for your own medicine and do not generalise to other tablets.
Medication
Is a weight loss pill as effective as an injection?
A pill is not inherently less effective than an injection, but trial averages from different studies cannot establish a direct comparison. Foundayo's reported trial result applies to a particular study population, dose, and timeframe, not a guaranteed individual outcome; treatment choice requires clinical discussion.
Medication
Who is Foundayo suitable for?
UK authorisation covers adults with insufficiently controlled type 2 diabetes and, separately, adult weight management at BMI 30 or above or BMI 27 to below 30 with a weight-related condition, alongside lifestyle measures. Eligibility does not establish personal suitability; a prescriber must consider the individual and current product information.
Medication
Can you switch from a weight loss injection to a tablet?
Some people may be able to switch from an injectable weight-loss medicine to Foundayo, but there is no universal safe schedule. Do not stop, overlap, or start medicines independently; the prescriber should plan timing, tolerability, and any diabetes monitoring.
Medication
Why do these medicines slow your stomach, and can you prevent it?
GLP-1 medicines slow stomach emptying, which can cause nausea, fullness, constipation, or, rarely, more serious motility problems; symptoms are not always preventable. Eat smaller meals and follow the prescriber's advice, and seek urgent assessment for severe persistent pain, repeated vomiting, or inability to keep fluids down.
Complex severe obesity
Why doesn't weight-loss medication work for everyone?
People vary in their response to semaglutide, and limited weight change does not necessarily mean they are biologically 'resistant.' Dose and duration, missed doses, other medicines, health conditions and individual biology can matter; review progress with a prescriber before changing treatment.
Let's find out what's right for you
Treatment is one option among several, and which one suits you depends on your history, your other conditions and what has been tried before. That is what the consultation is for.