It starts with a consultation
Nothing is prescribed without one.
Medications
Mounjaro
(Tirzepatide)
Once-weekly injection penA once-weekly dual-hormone medicine prescribed within specialist obesity care — never as a stand-alone answer.
Your care pathway
How treatment works here
A careful clinical assessment
A doctor reviews your medical history, current medicines, conditions and the factors driving your weight before any treatment is recommended.
Where treatment is appropriate
It is prescribed following your consultation. In the UK, treatment is dispensed by a licensed pharmacy and delivered to your address anywhere in the UK. In Chennai, it is collected in person from the clinic.
Reviewed before every supply
Nothing is issued on repeat without review. Before each supply you tell us how you are getting on, and a doctor reviews how you are responding, how you are tolerating treatment and anything that has changed before deciding.
What's Included
Your Mounjaro Prescription Includes
Doctor-reviewed prescription
Every prescription follows individual review by a doctor and stays under ongoing clinical supervision.
Live online sessions with Dr Raj
Patients are invited to regular online education evenings and live Q&A sessions, covering nutrition, muscle preservation, managing side effects and planning for the long term.
Support between appointments
You can tell us about side effects or concerns at any point between consultations, not only at your next appointment.
How you receive your treatment
In the UK, dispensed by a licensed pharmacy and delivered to your door anywhere in the UK with tracked delivery. In Chennai, collected in person from the clinic.
About the Medication
What is Mounjaro?
Mounjaro contains tirzepatide, a prescription medicine given as a once-weekly injection under the skin. It is licensed in the UK for weight management in adults who meet the criteria, and for type 2 diabetes.
Tirzepatide is a dual agonist: it acts on both the GIP and GLP-1 receptors. A head-to-head trial found greater average weight reduction with tirzepatide than semaglutide. Having two targets does not establish which medicine is best for an individual.
Suitability depends on your medical history, your other medicines, pregnancy plans and the balance of potential benefit and risk — which is exactly what a specialist consultation is for.
How Does It Work?
Dual hormone signalling
Tirzepatide mimics GIP and GLP-1, two gut hormones released after eating that influence appetite, fullness and insulin release.
Slower gastric emptying
Food leaves the stomach more slowly, so fullness lasts longer and post-meal glucose rises more gently.
Better insulin sensitivity
Glucose control often improves early, which is why diabetes and blood-pressure medicines may need adjusting during treatment.
Using the pen
How the weekly pen works
UK Mounjaro comes in a pre-filled multi-dose KwikPen holding four weekly doses. Your nurse or doctor teaches the dose-selection and injection technique before your first use.
- Four weekly dosesEach KwikPen holds four doses. Select the prescribed dose before each injection; there is no mixing.
- Subcutaneous injectionInjected into the fat layer of the abdomen, thigh or back of the upper arm — not into muscle.
- Rotate the siteChange the injection site each week to keep the tissue healthy.
- Same day each weekChoose a fixed day; if needed, the day can be moved as long as at least 72 hours have passed.
- Safe storage and disposalRefrigerate at 2–8°C before use; after first use, keep below 30°C for up to 30 days. Discard in the sharps bin after dose four or 30 days from first use, whichever comes first.
Clinical Evidence
How Effective is Mounjaro?
In the SURMOUNT-1 trial, adults with obesity taking tirzepatide alongside lifestyle support lost substantially more weight than those on placebo over 72 weeks. Trial averages describe groups, not individuals.
15%
Average reduction at 5mg
19.5%
Average reduction at 10mg
20.9%
Average reduction at 15mg
3.1%
Placebo
SURMOUNT-1, New England Journal of Medicine, 2022. Your own result depends on dose, tolerance, nutrition, activity and long-term support.
Dosing
How Do You Take Mounjaro?
Mounjaro is a once-weekly self-injection. Treatment starts low and increases gradually, normally at four-week intervals, so your body has time to adjust.
Most people find side effects are strongest in the days after a dose increase, which is why escalation is never rushed and always reviewed.
Do not change your dose unless your doctor has told you to.
Available Doses
2.5mg
5mg
7.5mg
10mg
12.5mg
15mg
2.5mg is a starting dose only. Maintenance is individual — some people do best at 5mg, others need to continue escalating.
Who Qualifies?
- Adults meeting the licensed BMI and health criteria
- A complete medical and medication review with no identified contraindication
- Willing to engage with nutrition, activity and monitoring
- Not pregnant or trying to conceive
Book a consultation
Discuss your care with the clinic that is right for you.
Potential Side Effects
Like all medicines, Mounjaro may cause side effects. Most are mild and settle as your body adjusts. Seek urgent medical help for severe, persistent abdominal pain, especially if it spreads to the back, with or without vomiting.
NauseaVomitingDiarrhoeaConstipationReduced appetiteFatigueIndigestionHeadache
Always read the Patient Information Leaflet. Contact your clinic or your doctor with any concerns.
Read the Mounjaro patient information leafletSpecialist Indications
How Mounjaro is used across metabolic conditions
Weight rarely travels alone. Below is where tirzepatide fits within each condition we treat, with published evidence you can read for yourself.
Complex severe obesity
Obesity driven by several overlapping causes — hormonal, medication-related, psychological and metabolic.
Read the condition pageWhere Mounjaro fits: One part of a coordinated plan built after blood tests and root-cause assessment, alongside nutrition, movement and psychological support.
Published evidence
Type 2 diabetes
Insulin resistance and raised blood glucose that often improve as weight and body composition change.
Read the condition pageWhere Mounjaro fits: Tirzepatide improves glucose control and weight together, so diabetes medicines frequently need reviewing and reducing during treatment.
Published evidence
Fatty liver disease (MASLD)
Fat accumulation in the liver that can progress to inflammation and fibrosis if left unaddressed.
Read the condition pageWhere Mounjaro fits: Sustained weight reduction is the strongest lever on liver fat; treatment sits alongside liver function tests and FibroScan monitoring.
Published evidence
Polycystic Ovary Syndrome (PCOS)
Polycystic Ovary Syndrome (PCOS) — insulin resistance, cycle disruption and androgen excess.
Read the condition pageWhere Mounjaro fits: Weight and insulin sensitivity improvements can help cycle regularity; contraception and pregnancy plans must be discussed first.
Published evidence
Fertility and conception
Weight and insulin resistance influence ovulation, sperm quality and the chance of conception.
Read the condition pageWhere Mounjaro fits: Used to prepare metabolic health before conception, then stopped in good time — tirzepatide must not be used in pregnancy.
Published evidence
Weight regain after treatment
Appetite signalling returns when GLP-1 treatment stops, and regain is common without a maintenance plan.
Read the condition pageWhere Mounjaro fits: Dose is tapered or maintained deliberately, with a structured maintenance plan rather than an abrupt stop.
Published evidence
More than a prescription
The Specialist Weight Management Plan
The Specialist Weight Management Plan is our most intensive option for the most complex cases. Dr Raj recommends it after your initial consultation where it is the right level of support. Not everyone needs it. For others, consultations and review alone are enough, and what you are offered depends on what is actually going on.
Mounjaro FAQs
From the clinic
Clinical Insights
Medication
Why do these medicines slow your stomach, and can you prevent it?
GLP-1 medicines slow stomach emptying, which can cause nausea, fullness, constipation, or, rarely, more serious motility problems; symptoms are not always preventable. Eat smaller meals and follow the prescriber's advice, and seek urgent assessment for severe persistent pain, repeated vomiting, or inability to keep fluids down.
Medication
Does Mounjaro help PCOS?
Mounjaro (tirzepatide) may improve weight and insulin-related features in some people with PCOS, but it is not a proven cure and evidence specific to PCOS is still developing. Discuss approved indications, contraception, pregnancy plans, and alternatives with a clinician; do not use it during pregnancy.
Medication
Can Mounjaro improve erectile dysfunction?
Mounjaro is not licensed specifically to treat erectile dysfunction, and any improvement would be indirect if metabolic health changes. Erectile dysfunction needs assessment for cardiovascular, diabetes, medication, and hormonal causes; do not delay evaluation while pursuing weight treatment.
Medication
Does Mounjaro help menopausal weight gain?
Mounjaro (tirzepatide) can support weight management for some people who meet prescribing criteria, including during or after menopause. It does not treat menopause or replace hormone therapy, and menopause-specific evidence is limited; discuss suitability and symptoms with a clinician.
Medication
Can Mounjaro affect your libido?
There is no strong evidence that Mounjaro directly raises or lowers sexual desire. Nausea, fatigue, mood, other medicines and health changes can affect libido; seek a review if a change persists or troubles you rather than changing treatment yourself.
Complex severe obesity
Why doesn't weight-loss medication work for everyone?
People vary in their response to semaglutide, and limited weight change does not necessarily mean they are biologically 'resistant.' Dose and duration, missed doses, other medicines, health conditions and individual biology can matter; review progress with a prescriber before changing treatment.
Let's find out what's right for you
Treatment is one option among several, and which one suits you depends on your history, your other conditions and what has been tried before. That is what the consultation is for.