Get Wegovy to help with
depression and weight gain

*In some cases, if the doctor requires more information, you may be asked to answer follow-up
questions or attend a 1-to-1 virtual consultation before a prescription is approved

Get Wegovy to help with
depression and weight gain

*In some cases, if the doctor requires more information, you may be asked to answer follow-up questions or attend a 1-to-1 virtual consultation before a prescription is approved

CONNECTION BETWEEN
DEPRESSION AND WEIGHT GAIN

Depression and obesity frequently occur together, forming a complex relationship in which each can
worsen the other. People experiencing depression may gain weight but people who are overweight or
obese are at a higher risk of developing depressive feelings due to low mood, confidence etc.

The coexistence of depression and obesity can be attributed to various factors, including:

  • Similar Genetics: Shared genetic predispositions may contribute to both conditions.

  • Hormonal Imbalances: Alterations in hormone regulation can influence mood and weight.

  • Immune-Inflammatory Activation: Inflammation within the body can affect both mental and physical
    health.

  • Altered Brain Circuits: Changes in brain function and mood responses play a role.

  • Metabolic Changes: Obesity and depression can impact glucose metabolism and blood flow in the brain.

CONNECTION BETWEEN
DEPRESSION AND WEIGHT GAIN

Depression and obesity frequently occur together, forming a complex relationship in which each can worsen the other. People experiencing depression may gain weight but people who are overweight or obese are at a higher risk of developing depressive feelings due to low mood, confidence etc.

The coexistence of depression and obesity can be attributed to various factors, including:

  • Similar Genetics: Shared genetic predispositions may contribute to both conditions.

     

  • Hormonal Imbalances: Alterations in hormone regulation can influence mood and weight.

     

  • Immune-Inflammatory Activation: Inflammation within the body can affect both mental and physical health.

     

  • Altered Brain Circuits: Changes in brain function and mood responses play a role.

     

  • Metabolic Changes: Obesity and depression can impact glucose metabolism and blood flow in the brain.

Why are overweight/obese people depressed?

Obesity and depression are interconnected. According to a meta-analysis, obese individuals have 55% higher risk of developing depression whilst depressed individuals have 58% higher risk of becoming obese. 

Obesity is an inflammatory condition where excess fat in the abdominal region releases pro-inflammatory cytokines, IL-6 and TNF-α and CRP. These cytokines can alter the brain neurotransmitters such as serotonin and dopamine, directly influencing mood. This altered brain chemistry creates a connection between depression and obesity. 

Hormonal imbalances also contribute to this interlink. Obesity often leads to leptin and insulin resistance, impairing both appetite control and emotional regulation. 

Elevated cortisol levels from chronic stress further promote fat storage and depressive symptoms. Environmental and lifestyle conditions also contribute. 

Stigma, body shaming, and low self-esteem can activate stress pathways such as the HPA axis, reinforcing emotional eating and anxiety. Poor sleep, inactivity, and diets high in processed food can disrupt the gut-brain axis.

HOW CAN WEGOVY BE PRESCRIBED FOR DEPRESSION/WEIGHT?

Wegovy may be useful in managing depression and weight by
supporting weight management. Obesity and depression are linked. As
Wegovy helps people with weight loss, the results may have a positive
effect on a persons wellbeing. After the doctor reviews the patient in a
consultation such as going over mental health, medications linked to
mental health, it will determine if the patient is suitable to be prescribed
Wegovy. The patient would start on the starter dose of 0.25mg if
approved for Wegovy.

HOW CAN WEGOVY BE PRESCRIBED FOR DEPRESSION/WEIGHT?

Wegovy may be useful in managing depression and weight by supporting weight management. Obesity and depression are linked. As Wegovy helps people with weight loss, the results may have a positive effect on a persons wellbeing. After the doctor reviews the patient in a consultation such as going over mental health, medications linked to mental health, it will determine if the patient is suitable to be prescribed Wegovy. The patient would start on the starter dose of 0.25mg if
approved for Wegovy.

HOW DOES WEGOVY WORK?

Semaglutide, a medication for type 2 diabetes, is marketed under the name Wegovy. Semaglutide are
members of the glucagon-like peptide-1 (GLP-1) receptor agonist drug class. These drugs imitate the
functions of the GLP-1 hormone, which aids in controlling body weight, food consumption, and hunger.
By slowing down the time it takes to digest the food consumed, it makes the person feel fuller for longer
which in turn reduces food intake. This accompanied with a healthy lifestyle will lead to successful
weight loss outcomes and in turn, can improve wellbeing.

HOW DOES WEGOVY WORK FOR DEPRESSION/WEIGHT?

Semaglutide, a medication for type 2 diabetes, is marketed under the name Wegovy. Semaglutide are members of the glucagon-like peptide-1 (GLP-1) receptor agonist drug class. These drugs imitate the functions of the GLP-1 hormone, which aids in controlling body weight, food consumption, and hunger. By slowing down the time it takes to digest the food consumed, it makes the person feel fuller for longer which in turn reduces food intake. This accompanied with a healthy lifestyle will lead to successful weight loss outcomes and in turn, can improve wellbeing.

WHAT ARE THE REQUIREMENTS
FOR WEGOVY?

Before recommending Wegovy for weight management, medical professionals will evaluate a number
of aspects, including general health and BMI. If the patient meets the eligibility requirements and the
medicine is deemed appropriate for managing their weight, they can be prescribed Wegovy. There
maybe a few factors preventing the prescribing of Wegovy such as Thyroid cancer or any medical
conditions which could be a health risk. The patient must be reviewed by a healthcare professional to
be reviewed for the suitability of the medication.

WHAT ARE THE REQUIREMENTS FOR WEGOVY?

Before recommending Wegovy for weight management, medical professionals will evaluate a number of aspects, including general health and BMI. If the patient meets the eligibility requirements and the medicine is deemed appropriate for managing their weight, they can be prescribed Wegovy. There maybe a few factors preventing the prescribing of Wegovy such as Thyroid cancer or any medical conditions which could be a health risk. The patient must be reviewed by a healthcare professional to be reviewed for the suitability of the medication.

COMPLETE YOUR
ONLINE SCREENING
FOR WEGOVY

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